Thor van Heesch

MDNA is a software module that generates and analyzes complex DNA structures, supporting modifications and providing geometric analysis tools for detailed DNA modeling.

This study shows that nuclear mechanostability arises from satellite DNA condensation into chromocenters, which help dissipate mechanical stress and protect genome integrity.

This study investigates the DNA-binding properties of bacterial histone HBb in Bdellovibrio bacteriovorus, revealing its ability to bend DNA in a sequence-independent manner, similar to archaeal and eukaryotic histones.