Author

Carlos A. Origel Marmolejo

Oregon Health & Science UniversityORCID 0000-0001-5091-3164Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Organism:mouse· 1

Frequent Co-Authors

Celina Sanchez· 2 shared Joshua C. SaldivariD· 2 shared Dmytro Grygoryev· 1 shared Dove J. Keith· 1 shared Elise C. ManaloiD· 1 shared Jinho LeeiD· 1 shared John L. MuschleriD· 1 shared Ju Young LeeiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersMolecular Biology

Celina Sanchez

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintMay 1, 2026

G2-to-G0 cell cycle exit underlies sensitivity to ATR inhibition via the p53-p21-RB1 axis

Celina Sanchez, Carlos A. Origel Marmolejo, Juyoung Lee, Joshua C. Saldivar

The paper identifies the p53-p21-RB1 axis as a determinant of breast cancer sensitivity to ATR inhibition, showing it drives G2-to-G0 cell cycle exit and is modulated by MDM2.

DOI 10.64898/2026.04.28.721427

humanstatistical model

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Cell BiologyCellular and Molecular Gastroenterology and HepatologyPeer-reviewedJan 1, 2025

HMG Box-Containing Protein 1 (HBP1) Protects Against Pancreatic Injury in Acute Pancreatitis but Promotes Neoplastic Progression.

Seung-Won Lee, Taelor J. Ekstrom, Elise C. Manalo…·Jungsun Kim

This study shows HBP1 protects against acute pancreatitis but promotes pancreatic cancer progression in the presence of KRAS mutations.

1 citation

mousehuman

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Molecular BiologybioRxivPreprintMay 10, 2024

A phosphorylation code coordinating transcription condensate dynamics with DNA replication

Carlos A. Origel Marmolejo, Celina Sanchez, Ju‐Young Lee…·Joshua C. Saldivar

This study identifies a phosphorylation code in MED1 that coordinates transcription condensate dynamics with DNA replication, showing its importance for histone biosynthesis and DNA damage prevention.

1 citation

humanproteomics

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