Author

Heejin Roh

Broad InstituteORCID 0000-0001-5100-689XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:ATAC-seq· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1 Organism:human· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Allison P. SiegenfeldiD· 2 shared Brian B. LiauiD· 2 shared Shelby A RosemaniD· 2 shared C. GuoiD· 1 shared Caroline ComenhoiD· 1 shared Ceejay LeeiD· 1 shared Corin WageniD· 1 shared Eric Zhou· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMolecular Biology

Allison P. SiegenfeldORCID

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2 papers

Recent·Most cited

Molecular BiologyNature MethodsPeer-reviewedSep 11, 2025

Coupling CRISPR Scanning with Targeted Chromatin Accessibility Profiling using a Double-Stranded DNA Deaminase

Heejin Roh, Simon P. Shen, Hu Yan…·Brian B. Liau

This paper introduces TDAC-seq, a method combining CRISPR perturbations with chromatin accessibility profiling to study cis-regulatory elements at single-nucleotide resolution.

9 citations

humanCRISPR screen

𝕏 PostBluesky

GenomicsNature CommunicationsPeer-reviewedJul 20, 2022

Polycomb-lamina antagonism partitions heterochromatin at the nuclear periphery

Allison P. Siegenfeld, Shelby A Roseman, Heejin Roh…·Brian B. Liau

The paper develops LIMe-Hi-C to study how Polycomb repressive complex 2 and lamina association regulate heterochromatin sub-compartments.

39 citations

Hi-Cexperimental assay

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