Author

Hu Yan

Broad InstituteORCID 0000-0002-8435-6586Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Allison P. SiegenfeldiD· 1 shared Brian B. LiauiD· 1 shared C. GuoiD· 1 shared Caroline ComenhoiD· 1 shared Ceejay LeeiD· 1 shared Heejin RohiD· 1 shared Hui Si KwokiD· 1 shared Jason Daniel BuenrostroiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Allison P. SiegenfeldORCID

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1 paper

Recent·Most cited

Coupling CRISPR Scanning with Targeted Chromatin Accessibility Profiling using a Double-Stranded DNA Deaminase

Heejin Roh, Simon P. Shen, Hu Yan, Hui Si Kwok, Allison P. Siegenfeld, Ceejay Lee, M. Lisandra Zepeda, C. Guo, Shelby A Roseman, Caroline Comenho, Vijay G. Sankaran, Jason Daniel Buenrostro, Brian B. Liau

This paper introduces TDAC-seq, a method combining CRISPR perturbations with chromatin accessibility profiling to study cis-regulatory elements at single-nucleotide resolution.

Nature Methods · Sep 11, 2025Peer-reviewedMolecular Biology