Molecular BiologybioRxivPreprint
3D Structure Determination of Protein Complexes using Matrix-Landing Mass Spectrometry
Michael S. Westphall, Kenneth W. Lee, Austin Z. Salome…·Joshua J. Coon
This paper introduces a modified mass spectrometry system for depositing gas-phase protein complexes onto EM grids, enabling 3D structure determination of non-covalent protein complexes like GroEL.