Author

Kenneth W. Lee

University of Wisconsin–MadisonORCID 0000-0003-4477-4553Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Joshua J. CooniD· 2 shared Michael S. WestphalliD· 2 shared Austin Z. SalomeiD· 1 shared Graeme C. McAlisteriD· 1 shared Jean M. LodgeiD· 1 shared John E. P. Syka· 1 shared Joshua D. HinkleiD· 1 shared Keaton L. MertziD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

Joshua J. CoonORCID

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2 papers

Recent·Most cited

BiochemistryJournal of Proteome ResearchPeer-reviewedMay 7, 2024

Boosting the Sensitivity of Quantitative Single-Cell Proteomics with Activated Ion-Tandem Mass Tags (AI-TMT)

Trenton M. Peters-Clarke, Yiran Liang, Keaton L. Mertz…·Joshua J. Coon

This paper introduces AI-TMT, a method enhancing single-cell proteomics sensitivity by improving reporter ion generation, resulting in higher signal and faster analysis.

14 citations

humanproteomics

𝕏 PostBluesky

Molecular BiologybioRxivPreprintOct 13, 2021

3D Structure Determination of Protein Complexes using Matrix-Landing Mass Spectrometry

Michael S. Westphall, Kenneth W. Lee, Austin Z. Salome…·Joshua J. Coon

This paper introduces a modified mass spectrometry system for depositing gas-phase protein complexes onto EM grids, enabling 3D structure determination of non-covalent protein complexes like GroEL.

3 citations

protein structureexperimental assay

𝕏 PostBluesky