Author

Philip S. Hobson

The Francis Crick InstituteORCID 0000-0001-5117-2994Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Aleksandra OlowiD· 1 shared Antonio RullaniD· 1 shared Beatriz Fuga Rossi TeixeiraiD· 1 shared Charles SwantoniD· 1 shared Chris MooreiD· 1 shared Claire E. PillsburyiD· 1 shared David NovoiD· 1 shared Deborah R. CaswelliD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Aleksandra OlowORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintNov 25, 2025

Oncogenic RAS activity is linked to immune priming and adenosine-driven immune evasion in lung adenocarcinoma

Sophie de Carné Trécesson, Philip East, Claire E. Pillsbury…·Julian Downward

This study links oncogenic RAS activity to immune priming and adenosine-driven immune evasion in lung adenocarcinoma, showing both pro-immunogenic and immunosuppressive effects.

DOI 10.1101/2025.11.25.690426

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintOct 23, 2025

Multicellular Calcium Waves in Cancer-Associated Fibroblasts Regulate Neuronal Mimicry and Anisotropy Leading to Immune Exclusion

Giovanni Giangreco, Zoe Ramsden, Antonio Rullan…·Erik A. Sahai

The paper identifies neuronal mimicry in cancer-associated fibroblasts driven by calcium waves, leading to immune exclusion, and shows that blocking this process restores immune control.

DOI 10.1101/2025.10.23.684281

humanbulk RNA-seq

𝕏 PostBluesky