Author

Katy A. McLaughlin

Wellcome Centre for Cell BiologyORCID 0000-0001-5128-1883Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Christina AmbrosiiD· 1 shared Christos SpanosiD· 1 shared Devisree ValsakumariD· 1 shared Elana BryaniD· 1 shared Juri RappsilberiD· 1 shared Kimberly M. WebbiD· 1 shared Marie Warburton· 1 shared Nwamaka J. IdigoiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Christina AmbrosiORCID

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1 paper

Recent·Most cited

Molecular BiologyMolecular CellPeer-reviewedDec 27, 2024

Nucleosomal Asymmetry Shapes Histone Mark Binding and Promotes Poising at Bivalent Domains

Elana Bryan, Devisree Valsakumar, Nwamaka J. Idigo…·Philipp Voigt

The paper shows that asymmetric bivalent nucleosomes at developmental gene promoters promote a poised state by recruiting repressive H3K27me3 binders and specific chromatin proteins like KAT6B, which is critical for ESC differentiation.

16 citations

mouseChIP-seq

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