Author

Elana Bryan

Wellcome Centre for Cell BiologyORCID 0000-0002-7925-2424Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Kimberly M. WebbiD· 2 shared Philipp VoigtiD· 2 shared Viktoria Major· 2 shared Christina AmbrosiiD· 1 shared Christos SpanosiD· 1 shared Devisree ValsakumariD· 1 shared Juri RappsilberiD· 1 shared Katy A. McLaughliniD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Kimberly M. WebbORCID

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2 papers

Recent·Most cited

Molecular BiologyMolecular CellPeer-reviewedDec 27, 2024

Nucleosomal Asymmetry Shapes Histone Mark Binding and Promotes Poising at Bivalent Domains

Elana Bryan, Devisree Valsakumar, Nwamaka J. Idigo…·Philipp Voigt

The paper shows that asymmetric bivalent nucleosomes at developmental gene promoters promote a poised state by recruiting repressive H3K27me3 binders and specific chromatin proteins like KAT6B, which is critical for ESC differentiation.

16 citations

mouseChIP-seq

𝕏 PostBluesky

Molecular BiologybioRxivPreprintJul 21, 2020

The TAZ2 domain of CBP/p300 directs acetylation towards H3K27 within chromatin

Thomas W. Sheahan, Viktoria Major, Kimberly M. Webb…·Philipp Voigt

This study identifies the TAZ2 domain of CBP/p300 as essential for directing acetylation towards H3K27 in chromatin, enhancing specificity and gene expression regulation.

6 citations

mouseChIP-seq

𝕏 PostBluesky