The paper uses polarized neutron scattering to study individual and collective fast dynamics in proteins, highlighting challenges in analyzing coherent scattering contributions.

Physical review. E · Sep 4, 2026Peer-reviewedBiophysics

Hydration and H/D exchange-dependent infrared signatures of the GCN4 leucine zipper

Hinduja Bhuvanendran, Carla M. Brunner, Hannes Kempf, Jonathan L. Moro, Eugenio Roubieu, Florian Turbant, André Mateus, H Y Lin, Lakshmi Das, Dmitry Malyshev, Ben Johns, Antonietta Parracino, Annalisa Pastore, Judith Peters, Aitziber L. Cortajarena, , Nicolò Maccaferri

This study uses vacuum-dried ATR-FTIR spectroscopy to analyze the structural features and HDX kinetics of GCN4, revealing distinct Amide I bands in dry samples.

bioRxiv · Jun 26, 2026 · PreprintBiochemistry

DNA supercoiling modulates bZIP transcription factor/DNA interaction

Rosanna Mattossovich, Rosa Merlo, Gioacchino Schifino, Annamaria Sandomenico, Mikael Widersten, Antonino Caliò, Judith Peters, Annalisa Pastore, Antonietta Parracino, Anna Valenti

This study shows DNA supercoiling affects GCN4-DNA binding stability and conformational dynamics through experimental and simulation approaches.

bioRxiv · May 7, 2026 · PreprintBiochemistry

DNA binding drives phase separation of the Gcn4 bZIP domain and reveals its conformational ensemble in the diluted and condensate phases

Antonino Caliò, Florian Turbant, Mark D. Tully, Satyan Sharma, Gioacchino Schifino, Antonietta Parracino, Judith Peters, Annalisa Pastore

bioRxiv · Feb 11, 2026 · PreprintBiophysics

Cytoplasmic Fluidity and the Cold Life: Proteome Stability is Decoupled from Viability in Psychrophiles

Beatrice Caviglia, Štěpán Timr, Marianne Guiral, Marie‐Thérèse Giudici‐Orticoni, Tilo Seydel, Christian Beck, Judith Peters, Fabio Sterpone, Alessandro Paciaroni

The paper investigates how protein diffusion and proteome stability change in psychrophilic and hyperthermophilic bacteria, finding that proteome dynamics decouple from viability in cold environments.

Nature Communications · Nov 24, 2025Peer-reviewedBiophysics

Bilayer-forming lipids enhance archaeal monolayer membrane stability

Margot Saracco, Philippe Schaeffer, Maxime Tourte, Sonja‐Verena Albers, Yoann Louis, Judith Peters, Bruno Demé, Stéphane Fontanay, Philippe Oger

This study shows that mixed diether and tetraether lipids improve archaeal membrane stability under thermal stress compared to pure lipid systems.

International Journal of Molecular Sciences · Mar 26, 2025Peer-reviewedBiophysics