Štěpán Timr

The paper investigates how protein diffusion and proteome stability change in psychrophilic and hyperthermophilic bacteria, finding that proteome dynamics decouple from viability in cold environments.

This study distinguishes stable and transient protein interfaces by analyzing their support regions, showing that differences lie in residue and interaction patterns rather than overall composition.

The paper measures two-photon absorptivity tensors of fluorescent proteins to understand their directionality and provides insights for biosensor development.

This study determines the cryoEM structures of human PFK1 in R- and T-states, revealing eukaryotic allosteric regulation mechanisms and the role of the C-terminus in autoinhibition.