Kiyohiko Igarashi

The paper develops a bioorthogonal fluorescence probe and engineered enzyme for low-background cancer imaging in mouse models.

The paper determines the crystal structure of a PcPOx mutant and shows how a tyrosine substitution disrupts covalent flavinylation, reducing enzyme activity.

The paper uses random forest machine learning to classify white- and brown-rot fungi based on CAZyme gene counts with over 98% accuracy.

The paper solves the crystal structures of Pc1,3Gal43A, an exo-β-1,3-galactanase from Phanerochaete chrysosporium, revealing its mechanism for bypassing side chains in arabinogalactan proteins.