Author

Raife Dilek Turan

Yeditepe UniversityORCID 0000-0001-5159-4775Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Esra AlbayrakiD· 2 shared Fatih KocabaşiD· 2 shared Galip Servet AslaniD· 2 shared Lamia Yazgi Alyazici· 2 shared Batuhan Mert KalkaniD· 1 shared Dogacan Yucel· 1 shared Doğacan YüceliD· 1 shared Emre Can Tuysuz· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersMolecular Biology

Esra AlbayrakORCID

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2 papers

Recent·Most cited

Development of Small Molecule MEIS Inhibitors that modulate HSC activity

Raife Dilek Turan, Esra Albayrak, Merve Uslu, Pınar Si̇yah, Lamia Yazgi Alyazici, Batuhan Mert Kalkan, Galip Servet Aslan, Doğacan Yücel, Merve Aksöz, Emre Can Tüysüz, Neslihan Meriç, Serdar Durdağı, Zafer Gülbaş, Fatih Kocabaş

The paper develops small molecule inhibitors of MEIS1 that modulate HSC activity and show efficacy in vitro and in vivo.

Scientific Reports · May 14, 2020Peer-reviewedMolecular Biology

c-Myc inhibition is critical for HSC expansion and Rad51 expression

Merve Aksoz, Esra Albayrak, Galip Servet Aslan, Raife Dilek Turan, Lamia Yazgi Alyazici, Pinar Siyah, Emre Can Tuysuz, Serli Canikyan, Dogacan Yucel, Neslihan Meric, Zafer Gulbas, Fikrettin Sahin, Fatih Kocabas

This study shows that c-Myc inhibition expands HSCs and increases Rad51 expression, while a cocktail of inhibitors enhances HSC maintenance and HDR gene expression.

bioRxiv · Sep 4, 2018 · PreprintCell Biology