Author

Galip Servet Aslan

Goethe University FrankfurtORCID 0000-0002-5084-1241Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Esra AlbayrakiD· 2 shared Fatih KocabaşiD· 2 shared Lamia Yazgi Alyazici· 2 shared Raife Dilek TuraniD· 2 shared Batuhan Mert KalkaniD· 1 shared Dennis HeckeriD· 1 shared Dogacan Yucel· 1 shared Doğacan YüceliD· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMolecular Biology

Esra AlbayrakORCID

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3 papers

Recent·Most cited

Developmental BiologyNature CommunicationsPeer-reviewedDec 2, 2022

The epigenetic modifier DOT1L regulates gene regulatory networks necessary for cardiac patterning and cardiomyocyte cell cycle withdrawal

Paola Cattaneo, Michael G.B. Hayes, Nina Baumgarten…·Sylvia Μ. Evans

This study shows that DOT1L regulates specific gene networks in cardiac development and cell cycle withdrawal through H3K79me2 modifications.

26 citations

mousebulk RNA-seq

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Molecular BiologyScientific ReportsPeer-reviewedMay 14, 2020

Development of Small Molecule MEIS Inhibitors that modulate HSC activity

Raife Dilek Turan, Esra Albayrak, Merve Uslu…·Fatih Kocabaş

The paper develops small molecule inhibitors of MEIS1 that modulate HSC activity and show efficacy in vitro and in vivo.

41 citations

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Cell BiologybioRxivPreprintSep 4, 2018

c-Myc inhibition is critical for HSC expansion and Rad51 expression

Merve Aksoz, Esra Albayrak, Galip Servet Aslan…·Fatih Kocabas

This study shows that c-Myc inhibition expands HSCs and increases Rad51 expression, while a cocktail of inhibitors enhances HSC maintenance and HDR gene expression.

DOI 10.1101/403584

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