Author

Merve Uslu

Johns Hopkins UniversityORCID 0000-0002-5410-7052Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 2 Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:drug response / drug discovery· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Martin TrapečariD· 3 shared Mohd Farhan SiddiquiiD· 3 shared Douglas K. BrubakeriD· 2 shared Luther Raechal· 2 shared Matjaz Dogsa· 2 shared Ran RaniD· 2 shared Andrea Mcpherson· 1 shared Batuhan Mert KalkaniD· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersBioengineering

Martin TrapečarORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

BioengineeringbioRxivPreprintMay 27, 2026

Inter-organ communication shapes human metabolic tissue states and resolves anti-diabetic drug response modes in a six-tissue microphysiological system

Marissa I. McGilvrey, Shereen Chew, Mohd Farhan Siddiqui…·Martin Trapečar

This study develops a six-tissue microphysiological system to investigate how inter-organ communication and nutrient conditions influence metabolic tissue states and drug responses to anti-diabetic therapies.

DOI 10.64898/2026.05.22.726943

humanbulk RNA-seq

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BioengineeringbioRxivPreprintMay 5, 2025

Personalized Gut-Liver Microphysiological System Maps Donor-Specific Tissue Resident Immunity and Reveals a Conserved Metabolic Crosstalk

Merve Uslu, Ran Ran, Mohd Farhan Siddiqui…·Martin Trapečar

The paper builds a personalized gut-liver microphysiological system to study donor-specific immune profiles and reveals a conserved metabolic crosstalk between gut and liver.

DOI 10.1101/2025.05.05.652244

humanscRNA-seq

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ImmunologybioRxivPreprintMar 11, 2025

Single-Cell Analysis Reveals Tissue-Specific T Cell Adaptation and Clonal Distribution Across the Human Gut-Liver-Blood Axis

Ran Ran, Merve Uslu, Mohd Farhan Siddiqui…·Martin Trapečar

The paper tracks T cell clones across gut, liver, and blood using single-cell RNA and TCR sequencing, revealing tissue-specific adaptations and limited overlap between colonic IELs and lamina propria T cells.

2 citations

humanscRNA-seq

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Molecular BiologyScientific ReportsPeer-reviewedMay 14, 2020

Development of Small Molecule MEIS Inhibitors that modulate HSC activity

Raife Dilek Turan, Esra Albayrak, Merve Uslu…·Fatih Kocabaş

The paper develops small molecule inhibitors of MEIS1 that modulate HSC activity and show efficacy in vitro and in vivo.

41 citations

mousehuman

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