Ana Paula Pêgo

This study identifies a dual-phase enhancer that maintains pancreatic progenitor cells and stabilizes lineage identity, preventing pathological plasticity and disease.

This study develops neuron-targeted dendriplexes for siRNA delivery, showing enhanced axonal growth and CNS targeting in a PNS-CNS-on-Chip model.

This paper develops a chitosan-based nanocarrier for targeted siRNA delivery to neurons, showing enhanced axonal growth by downregulating PTEN.

This paper develops a tissue-engineered model to study how physical cues like stiffness and axonal diameter affect oligodendrocyte myelination, finding that softer substrates promote differentiation while rigid ones maintain mature states.