Eran Perlson

This study develops neuron-targeted dendriplexes for siRNA delivery, showing enhanced axonal growth and CNS targeting in a PNS-CNS-on-Chip model.

This study shows that acetylation of G3BP1 by ELP3 promotes axon regeneration and neuronal recovery after injury.

The paper shows that axonal mTOR-dependent Rab5 translation is essential for BDNF signaling and retrograde transport to the nucleus.

This paper develops a chitosan-based nanocarrier for targeted siRNA delivery to neurons, showing enhanced axonal growth by downregulating PTEN.

This study shows CRMP2 is essential for Sema3F-dependent axon pruning and dendritic spine remodeling, linking its dysfunction to ASD-like behaviors in mice.

The paper identifies a novel retrograde death signal mechanism in ALS motor neurons involving CRMP4-dynein complex formation triggered by muscle-secreted Sema3A.