Pashupati Prasad Mishra

This study compares traditional risk factors and epigenetic clocks in predicting non-communicable disease morbidity and finds traditional factors perform better in a middle-aged cohort.

The paper maps cis- and trans-eQTLs in blood samples to infer gene regulatory networks and prioritize trait-relevant pathways.

This study shows that disrupting non-canonical autophagy (LANDO) impairs endothelial and cardiac function by disrupting VEGFR2 recycling and Hb- expression.

The paper identifies USP18 as a negative regulator of interferon response at a lupus risk locus through trans-eQTL analysis in lymphoblastoid cell lines.

This study shows that a genetic risk score for coronary artery calcification improves CAD prediction beyond traditional risk factors in three European cohorts.

This study identifies 400+ genetic loci associated with circulating metabolic traits and highlights pleiotropy and novel disease pathways.

The paper examines nc886 methylation across populations and tissues, finding stable levels except in specific tissues and some discordance in dizygotic twins.

The paper examines nc886 methylation patterns across mammals, finding non-conserved imprinting and methylation status, suggesting limited use of animal models for nc886 research.

This paper identifies DNA methylation sites associated with aggression through a meta-analysis of epigenome-wide studies across different age groups and tissues.

This study identifies 137 genome-wide significant loci associated with DNA methylation biomarkers of ageing using DNAm and SNP data from over 41,000 individuals.

This study identifies 210 genetic loci associated with the PR interval through multi-ancestry GWAS, highlighting their role in cardiac conduction and cardiovascular disease.