Suresh Poudel

This study identifies tissue-specific proteomic changes in a Drosophila SCA17 model, showing polyglutamine-expanded TBP affects pathways beyond transcription.

The paper classifies human Th17 cells into non-pathogenic and pathogenic states and identifies acylcarnitine metabolism as a vulnerability in type 2 diabetes.

MakeMyFigure enables reproducible scientific figure creation by integrating data analysis, visualization, and figure assembly in a single workflow with automated documentation.

This study shows that disrupting non-canonical autophagy (LANDO) impairs endothelial and cardiac function by disrupting VEGFR2 recycling and Hb- expression.

The paper shows that early arginine methylation of KCa3.1 limits Ca2+-mediated NFAT1 activation, preventing T cell exhaustion during activation.

Alzheimer's mouse model proteomes capture 30% (amyloid-only models) to 42% (adding tau and splicing models) of consensus human AD protein changes; in 5xFAD, plaques slow degradation of plaque-associated proteins.

The paper identifies an AD-like subtype in brain aging across multiple regions, showing overlap with AD gene signatures and regional differences in gene expression.