Siddhansh Agarwal

This study shows influenza A virus actively transports itself by modifying its environment, using its envelope proteins to create directional cues and bias movement.

The paper develops a bead-based Cas13a assay called SurfCas for sensitive and multiplexed RNA detection, showing it matches bulk reaction sensitivity and works in complex biological samples.

SurFlex microscopy quantifies flexibility of surface-tethered biomolecules using fluorescence anisotropy, revealing sequence-dependent DNA flexibility and changes in glycan flexibility on cell surfaces.

This study shows influenza A viruses use a burnt-bridge Brownian ratchet mechanism for directed motion through mucus, operating in an optimal parameter range due to evolutionary adaptation.