Author

Jordan Abettan

Biogen (United States)ORCID 0000-0001-5193-1479Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

Ana Claudia Silva AmaraliD· 2 shared Dominic M. WalshiD· 2 shared Edward D. PloweyiD· 2 shared Jennifer SebaluskyiD· 2 shared Ming Lye‐Barthel· 2 shared Paul H. WeinrebiD· 2 shared Thierry BussièreiD· 2 shared Adam P. SilvermaniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Ana Claudia Silva AmaralORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintFeb 2, 2026

An in vivo model of Amyloid-Related Imaging Abnormalities (ARIA) predicts ARIA incidence of anti-Aβ antibodies seen in clinical trials

Edward D. Plowey, Jordan Abettan, Peter Cheng‐te Chou…·Thierry Bussière

The paper uses a mouse model to study ARIA induced by anti-Aβ antibodies, showing MRI and histopathologic features similar to human ARIA.

1 citation

𝕏 PostBluesky

NeurosciencebioRxivPreprintJul 26, 2024

Engineering anti-amyloid antibodies with transferrin receptor targeting improves brain biodistribution and mitigates ARIA

Michelle E. Pizzo, Edward D. Plowey, Nathalie Khoury…·Y. Joy Yu Zuchero

This study develops an antibody transport vehicle targeting the transferrin receptor to improve brain delivery of anti-amyloid antibodies, reducing ARIA-like lesions and vascular inflammation in a mouse model.

13 citations

mouseproteomics

𝕏 PostBluesky