Author

Marisol Morales

The University of Texas at San Antonio Health Science CenterORCID 0000-0001-5206-2738Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Bibekananda SahooiD· 1 shared Fushun ZhangiD· 1 shared Xinghong DaiiD· 1 shared Yan XiangiD· 1 shared Zongjun MouiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperBiophysics

Bibekananda SahooORCID

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1 paper

Recent·Most cited

BiophysicsScience AdvancesPeer-reviewedSep 23, 2026

Structural Mechanisms of SAMD9 Autoinhibition and Pathogenic Dysregulation

Zongjun Mou, Fushun Zhang, Marisol Morales…·Yan Xiang

This study determines the structural basis of SAMD9 autoinhibition and explains how pathogenic mutations disrupt this mechanism to cause disease.

DOI 10.1126/sciadv.aeg3967

humancryo-EM

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