Mykola Roiuk

The paper identifies DCP2 as an ISR-induced transcript whose translation is regulated by an overlapping ORF that acts as an inhibitory element, which is relieved during stress.

This study investigates the role of eIF2A in translation initiation and uORF-mediated control in HeLa cells using ribosome profiling and luciferase assays, finding no detectable role in initiation.

This study shows that loss of Elp1 in cerebellar granule cell progenitors causes ataxia and cerebellar defects in mice, suggesting a role for ELP1 in FD pathogenesis.

The paper shows that niche signals regulate eIF3d1 phosphorylation to control translation initiation in stem and differentiating cells, enabling distinct translational programs.

This study identifies PRRC2 proteins as regulators of leaky scanning during translation initiation, enhancing translation of mRNAs with upstream open reading frames.

The paper shows that RPS6 phosphorylation decreases during mRNA translation, affecting translation efficiency more for short CDS mRNAs than long ones.