Author

Nydia P. Chang

Rutgers, The State University of New Jersey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Neuroscience· 3 Genomics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Brian P. DanielsiD· 3 shared Colm AtkinsiD· 3 shared Marissa LindmaniD· 3 shared Tsui-Wen ChouiD· 3 shared Irving EsteveziD· 2 shared Po-Lun Kung· 2 shared Abigail F. GroffiD· 1 shared Aisha P. Patel· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersNeuroscience

Brian P. DanielsORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Neuronal DAMPs exacerbate neurodegeneration via astrocytic RIPK3 signaling

Nydia P. Chang, Evan M. DaPrano, Marissa Lindman, Irving Estevez, Tsui-Wen Chou, Wesley R. Evans, Marialaina Nissenbaum, Micheal McCourt, Diego Alzate, Colm Atkins, Alexander W. Kusnecov, Rafiq Huda, Brian P. Daniels

This study shows that neuronal DAMPs activate astrocytic RIPK3 signaling, leading to neuroinflammation and dopaminergic cell death in Parkinson's disease.

JCI Insight · May 7, 2024Peer-reviewedNeuroscience

Zika virus-induced TNF-α signaling dysregulates expression of neurologic genes associated with psychiatric disorders

Po-Lun Kung, Tsui-Wen Chou, Marissa Lindman, Nydia P. Chang, Irving Estevez, Benjamin D. Buckley, Colm Atkins, Brian P. Daniels

This study shows ZIKV infection alters neurologic gene expression linked to psychiatric disorders through TNF-α signaling in neurons and mouse models.

Journal of Neuroinflammation · Apr 24, 2022Peer-reviewedNeuroscience

Fibrillar α-synuclein induces neurotoxic astrocyte activation via RIP kinase signaling and NF-κB

Tsui-Wen Chou, Nydia P. Chang, Medha Krishnagiri, Aisha P. Patel, Marissa Lindman, Juan P. Angel, Po-Lun Kung, Colm Atkins, Brian P. Daniels

This study shows that α-synuclein fibrils activate midbrain astrocytes through RIP kinase and NF-κB signaling, leading to neurotoxicity and inflammation in Parkinson's disease.

Cell Death and Disease · Jul 31, 2021Peer-reviewedNeuroscience

The Tug1 Locus is Essential for Male Fertility

Jordan P. Lewandowski, Gabrijela Dumbović, Audrey R. Watson, Taeyoung Hwang, Emily Jacobs-Palmer, Nydia P. Chang, Christian Much, Kyle M. Turner, Christopher Kirby, Jana Felicitas Schulz, Clara-Louisa Müller, Nimrod Daniel Rubinstein, Abigail F. Groff, Steve C. Liapis, Chiara Gerhardinger, , John L. Rinn

The paper identifies Tug1 as essential for male fertility, showing it has three distinct regulatory activities: a cis DNA repressor, a trans-acting lncRNA, and a conserved peptide affecting mitochondrial function.

bioRxiv · Feb 28, 2019 · PreprintGenomics