Spatial imprints of emergent cardiomyocyte states in the pressure-overloaded heart
Yuening Liu, Annabelle M. Coles, Jonah Castiglione, Vijay Venu Thiyagarajan, Kalen Clifton, Deevanshu Goyal, Jerry Wu, Arlo Sheridan, Ana Vujić, Kristen M. Harris, Uri Manor, Talmo Pereira, Jean Fan, Richard Theodore Lee, Pallav Kosuri
The paper uses spatial transcriptomics to analyze cardiomyocyte states in pressure-overloaded mouse hearts, finding pro-fibrotic states linked to microenvironmental changes.
bioRxiv · May 8, 2026 · PreprintGenomics