Author

Izabella Agostinho Pena

Massachusetts Institute of TechnologyORCID 0000-0001-5242-3724Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1 Approach:graph neural network· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Adelaide Maria Fernandes Borralho· 1 shared Alain Geille· 1 shared Albert Carbonell· 1 shared Alessandro PrigioneiD· 1 shared Alex Garanto· 1 shared Alex Mackenzie· 1 shared Alicia M. DarnelliD· 1 shared Anastasia KritharaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperBioinformatics

Adelaide Maria Fernandes Borralho

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2 papers

Recent·Most cited

BioinformaticsBioinformaticsPeer-reviewedMay 7, 2026

KG-Bench: Benchmarking Graph Neural Network Algorithms for Drug Repurposing

Siqi Wei, Christo Sasi, Jelle Piepenbrock…·Sara Pintado

KG-Bench benchmarks graph neural networks for drug repurposing using the Open Targets dataset, finding TransformerConv achieves the highest performance.

DOI 10.1093/bioinformatics/btag159

graph neural networkbenchmarking

𝕏 PostBluesky

BiochemistrybioRxivPreprintJun 18, 2025

Sideroflexins enable mitochondrial transport and metabolism of neutral amino acids

Samuel Block, Fangtao Chi, Paul C. Rosen…·Matthew G. Vander Heiden

The paper identifies sideroflexins as mitochondrial transporters for neutral amino acids and shows functional overlap among paralogues.

4 citations

humanproteomics

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