Author

Paul C. Rosen

Howard Hughes Medical InstituteORCID 0000-0001-7414-454XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Assay:imaging· 2 Research Focus:spatial domain detection· 2 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Bart LodderiD· 2 shared Bernardo Luis SabatiniiD· 2 shared Iso Hartman· 2 shared Joshua Timmins· 2 shared Michelle Siegel· 2 shared Roger A.H. AdaniD· 2 shared Tarun V. KamathiD· 2 shared Alicia M. DarnelliD· 1 shared

Activity by Year

2025-2025 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersNeuroscience

Bart LodderORCID

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4 papers

Recent·Most cited

NeurosciencebioRxivPreprintDec 25, 2025

Rapid fluorescence lifetime sensor development of LifeCamp enables transient and baseline absolute calcium measurements

Bart Lodder, Michelle Raghubardayal, Sanika Ganesh…·Bernardo Luis Sabatini

This paper introduces LifeCamp, a high-speed calcium lifetime sensor developed using RALISED, enabling accurate measurement of baseline and transient calcium levels in neurons.

DOI 10.64898/2025.12.23.696288

mouseimaging

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NeuroscienceNeuronPeer-reviewedSep 11, 2025

Absolute measurement of fast and slow neuronal signals with fluorescence lifetime photometry at high temporal resolution

Bart Lodder, Tarun V. Kamath, Ecaterina Savenco…·Bernardo Luis Sabatini

The paper develops FLIPR, a system for absolute fluorescence lifetime measurement in mice, revealing spatial and temporal variations in dopamine signaling.

17 citationstop 3%

mouseimaging

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Cell BiologyProceedings of the National Academy of SciencesPeer-reviewedSep 2, 2025

Lysosomal reduced thiols are essential for mouse embryonic development

Charles H. Adelmann, Avanthika Venkatachalam, Lingjuan Huang…·David E. Fisher

This study shows that MFSD12 is essential for mouse embryonic development by supplying reduced cysteine to lysosomes, and cysteamine treatment rescues Mfsd12 knockout mice.

2 citations

mouseexperimental assay

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BiochemistrybioRxivPreprintJun 18, 2025

Sideroflexins enable mitochondrial transport and metabolism of neutral amino acids

Samuel Block, Fangtao Chi, Paul C. Rosen…·Matthew G. Vander Heiden

The paper identifies sideroflexins as mitochondrial transporters for neutral amino acids and shows functional overlap among paralogues.

4 citations

humanproteomics

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