ImmunologyProceedings of the National Academy of SciencesPeer-reviewed
Complement C3d enables protective immunity capable of distinguishing spontaneously transformed from non-transformed cells
Jeffrey L. Platt, Chong Zhao, Jeffrey Chicca…·Marília Cascalho
This study shows that intracellular C3d enhances immune surveillance by inducing T cell responses against malignant plasma cells while sparing normal cells in a murine model of multiple myeloma.
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