Author

Marília Cascalho

University of MichiganORCID 0000-0002-2695-3921Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Ansen Tan· 1 shared Ariella ShikanoviD· 1 shared Arvind Rao· 1 shared Bipasha RayiD· 1 shared Chong ZhaoiD· 1 shared Delaney S Sinko· 1 shared Evan A. FarkashiD· 1 shared Evan T. KelleriD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBioengineering

Ansen Tan

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2 papers

Recent·Most cited

BioengineeringScience AdvancesPeer-reviewedJan 1, 2026

Restoration of ovarian endocrine function with encapsulated immune isolated human ovarian xenograft in ovariectomized mice

Margaret A. Brunette, Monica A. Rionda, Delaney S Sinko…·Ariella Shikanov

This study shows that encapsulated human ovarian xenografts restore endocrine function in ovariectomized mice, integrating with the host's hypothalamus-pituitary-gonad axis and maintaining cyclicity and hormone levels.

6 citationstop 1%

mouseexperimental assay

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ImmunologyProceedings of the National Academy of SciencesPeer-reviewedDec 18, 2024

Complement C3d enables protective immunity capable of distinguishing spontaneously transformed from non-transformed cells

Jeffrey L. Platt, Chong Zhao, Jeffrey Chicca…·Marília Cascalho

This study shows that intracellular C3d enhances immune surveillance by inducing T cell responses against malignant plasma cells while sparing normal cells in a murine model of multiple myeloma.

4 citations

mousebulk RNA-seq

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