Author

Jeffrey Chicca

University of Massachusetts Chan Medical SchoolORCID 0009-0009-5153-5914Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Amy M. WeeksiD· 1 shared Arvind Rao· 1 shared Barbora PafčoiD· 1 shared Carli Garceau· 1 shared Chong ZhaoiD· 1 shared E. Jane HomaniD· 1 shared Erich M. SchwarziD· 1 shared Evan A. FarkashiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenomics

Amy M. WeeksORCID

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2 papers

Recent·Most cited

GenomicsPLoS neglected tropical diseasesPeer-reviewedMar 17, 2026

Hookworm genes encoding intestinal excreted-secreted proteins are transcriptionally upregulated in response to the host's immune system

Erich M. Schwarz, Jason Noon, Jeffrey Chicca…·Raffi V. Aroian

The paper identifies hookworm genes upregulated by the host immune system, focusing on intestinal-expressed genes in A. ceylanicum and their potential roles in immune evasion.

3 citationstop 2%

mousebulk RNA-seq

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ImmunologyProceedings of the National Academy of SciencesPeer-reviewedDec 18, 2024

Complement C3d enables protective immunity capable of distinguishing spontaneously transformed from non-transformed cells

Jeffrey L. Platt, Chong Zhao, Jeffrey Chicca…·Marília Cascalho

This study shows that intracellular C3d enhances immune surveillance by inducing T cell responses against malignant plasma cells while sparing normal cells in a murine model of multiple myeloma.

4 citations

mousebulk RNA-seq

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