Federico Iovino

This study develops bioengineered extracellular vesicles that neutralize pneumolysin and reduce inflammation in pneumococcal meningitis, improving survival in a mouse model.

This study shows that bacteriophage-derived endolysin Cpl-1 restores antibiotic susceptibility in penicillin- and erythromycin-resistant Streptococcus pneumoniae infections in vitro and in vivo.

This study investigates the spatio-temporal invasion pattern of Streptococcus pneumoniae in the brain during meningitis and its impact on cellular environments.

This study shows pneumococcal meningitis impairs the glymphatic system, leading to bacterial accumulation in CSF and neuronal damage due to AQP4 misplacement.