Author

Kristine Farmen

Karolinska InstitutetORCID 0000-0002-3004-7462Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Federico IovinoiD· 3 shared Miguel Tofiño-VianiD· 2 shared Doste Rashid MamandiD· 1 shared Georgia Yfanti· 1 shared Katrin Wellfelt· 1 shared Lars Olson· 1 shared Lisa Knörr· 1 shared Niels Vander ElstiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersNeuroscience

Federico IovinoORCID

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3 papers

Recent·Most cited

NeuroscienceJournal of Extracellular VesiclesPeer-reviewedSep 1, 2026

Bioengineered extracellular vesicles mitigate neuroinflammation by neutralizing pneumolysin and delaying disease onset in experimental pneumococcal meningitis

Kristine Farmen, Doste Rashid Mamand, Miguel Tofiño-Vian…·Federico Iovino

This study develops bioengineered extracellular vesicles that neutralize pneumolysin and reduce inflammation in pneumococcal meningitis, improving survival in a mouse model.

1 citation

mouseexperimental assay

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MicrobiologybioRxivPreprintMar 18, 2025

Bacteriophage-derived endolysins restore antibiotic susceptibility in penicillin- and erythromycin-resistant Streptococcus pneumoniae infections

Niels Vander Elst, Lisa Knörr, Kristine Farmen, Federico Iovino

This study shows that bacteriophage-derived endolysin Cpl-1 restores antibiotic susceptibility in penicillin- and erythromycin-resistant Streptococcus pneumoniae infections in vitro and in vivo.

DOI 10.1101/2025.03.18.644011

humanmouse

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NeurosciencebioRxivPreprintOct 30, 2023

Spatio-temporal brain invasion pattern of Streptococcus pneumoniae and dynamic changes of the cellular environment in meningitis pathogenesis.

Kristine Farmen, Miguel Tofiño-Vian, Katrin Wellfelt…·Federico Iovino

This study investigates the spatio-temporal invasion pattern of Streptococcus pneumoniae in the brain during meningitis and its impact on cellular environments.

DOI 10.1101/2023.10.30.564671

mouseimaging

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