Parveen Sharma

BeatRatePy quantifies beat rate, contraction, and speed from label-free cardiac imaging data, showing consistent performance across different systems and datasets.

This study investigates the role of lysosomal Ca2+ signaling in heart rhythm and atrial function, finding that NAADP pathway inhibition affects SAN pacemaker activity and cAMP production in atrial myocytes.

The paper identifies a plasma RNA signature linked to MAPK14-related inflammatory signaling as a potential marker for postoperative atrial fibrillation susceptibility.

The paper uses IVIS Lysotracker imaging and RT-qPCR to assess lysosomal abundance and autophagy-related gene expression in young and aged mouse hearts, finding preserved acidic-vesicle pool and stable gene expression.

This study shows that CDDO-Me activates NRF2 to protect AC16 human cardiomyocytes from doxorubicin-induced toxicity by modulating p53 signaling, apoptosis, and ferroptosis.

This paper introduces a 3D HepG2/C3A liver spheroid model that supports the complete intrahepatocytic lifecycle of Plasmodium falciparum, offering an accessible and reproducible alternative to existing models.