Author

Thomas Labadie

Centre National de la Recherche ScientifiqueORCID 0000-0001-5263-3895Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Dorothée MisséiD· 1 shared Guillaume CambrayiD· 1 shared Isabelle Moltini-ConcloisiD· 1 shared Joanna ReiD· 1 shared Karim MajzoubiD· 1 shared Marie Motos· 1 shared Morgane ChemariniD· 1 shared Moritz SchüssleriD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperImmunology

Dorothée MisséORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJul 10, 2026

The RLR-MAVS-IRF3 axis activates the IFN pathway to restrict Tonate virus (TONV) infection

Thomas Labadie, Roger-Junior Eloiflin, Zoé Denis…·Karim Majzoub

This study identifies the RIG-I/MDA5-MAVS-IRF3 axis as the pathway sensing TONV infection and activating the IFN-I response to restrict viral replication.

DOI 10.64898/2026.07.09.737427

humanbulk RNA-seq

𝕏 PostBluesky

MicrobiologybioRxivPreprintJan 15, 2024

Selective manipulation of the host RNA-polymerase transcription fidelity increases phenotypic mutations in an insect Parvovirus

Thomas Labadie, Guillaume Cambray

The paper shows that a virus manipulates host transcription fidelity to generate non-heritable mutations, increasing phenotypic diversity for adaptation.

DOI 10.1101/2024.01.15.575645

DNA methylationproteomics

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