Author

Michael D. Brasino

Oregon Health & Science UniversityORCID 0000-0001-5264-6442Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

Eli WagnelliD· 2 shared Justin L. MerrittiD· 2 shared E. Sıla ÖzdemiriD· 1 shared Elise C. ManaloiD· 1 shared Jared Michael FischeriD· 1 shared Samuel L. DrennaniD· 1 shared Srivathsan Ranganathan· 1 shared

Activity by Year

2023-2024 · peak 1/yr

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7 top collaborators · 15 mutual co-author links

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2 shared papersSynthetic Biology

Eli WagnellORCID

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2 papers

Recent·Most cited

Synthetic BiologyMicrobiology SpectrumPeer-reviewedApr 30, 2024

Mutation of the peptide-regulated transcription factor ComR for amidated peptide specificity and heterologous function in Lactiplantibacillus plantarum WCFS1

Michael D. Brasino, Eli Wagnell, E. Sıla Özdemir…·Justin L. Merritt

The paper identifies ComR mutations that enhance specificity for amidated peptides, enabling potential use in biosensor applications.

1 citation

experimental assay

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Synthetic BiologybioRxivPreprintSep 27, 2023

Engineered Lactiplantibacillus plantarum as a Biosensor Probe for the Lungs

Michael D. Brasino, Eli Wagnell, Elise C. Manalo…·Justin L. Merritt

This paper demonstrates a genetically engineered Lactiplantibacillus plantarum strain as a biosensor for detecting lung disease by secreting a detectable biomarker in urine.

DOI 10.1101/2023.09.27.559779

mouseexperimental assay

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