Jared Michael Fischer

This study investigates how lipid tail length in peptide amphiphile nanostructures affects their interactions with biological systems, showing that molecular design can control biointeractions and tumor accumulation.

This study identifies RUNX1 as a key driver of tumor-immune hybrid cell invasion and dissemination in colorectal cancer, highlighting circulating hybrid cells as a biomarker for metastasis.

This study identifies MYST acetyltransferases as therapeutic targets in SETBP1-mutant leukemia, showing that MYST inhibitors reduce target gene expression and improve survival in mouse models.

This study demonstrates that peptide amphiphile nanostructures enhance cancer imaging and therapy by hitchhiking on endogenous biomolecules to target tumors effectively.

The paper examines microbial DNA in blood fractions, showing most is cell-free and reveals disease-associated differences in plasma and buffy coat.

This paper demonstrates a genetically engineered Lactiplantibacillus plantarum strain as a biosensor for detecting lung disease by secreting a detectable biomarker in urine.

The paper identifies a dual state of Bmi1-expressing intestinal stem cells that drive epithelial development and tissue regeneration through dynamic Wnt signaling.