Author

Eli Wagnell

Oregon Health & Science UniversityORCID 0000-0001-8418-5257Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

E. Sıla ÖzdemiriD· 2 shared Justin L. MerrittiD· 2 shared Michael D. BrasinoiD· 2 shared Bruce P. BranchaudiD· 1 shared Elise C. ManaloiD· 1 shared Florian Goncalves· 1 shared Jared Michael FischeriD· 1 shared Jessica Tolley· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersBioengineering

E. Sıla ÖzdemirORCID

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3 papers

Recent·Most cited

BioengineeringBiophysicaPeer-reviewedNov 27, 2024

A computationally guided approach to improve expression of VHH binders

E. Sıla Özdemir, Jessica Tolley, Florian Goncalves…·Srivathsan V. Ranganathan

This paper improves VHH binder expression through computational modeling of hydrophobic hotspots and guided mutagenesis.

2 citations

proteomicsdeep learning

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Synthetic BiologyMicrobiology SpectrumPeer-reviewedApr 30, 2024

Mutation of the peptide-regulated transcription factor ComR for amidated peptide specificity and heterologous function in Lactiplantibacillus plantarum WCFS1

Michael D. Brasino, Eli Wagnell, E. Sıla Özdemir…·Justin L. Merritt

The paper identifies ComR mutations that enhance specificity for amidated peptides, enabling potential use in biosensor applications.

1 citation

experimental assay

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Synthetic BiologybioRxivPreprintSep 27, 2023

Engineered Lactiplantibacillus plantarum as a Biosensor Probe for the Lungs

Michael D. Brasino, Eli Wagnell, Elise C. Manalo…·Justin L. Merritt

This paper demonstrates a genetically engineered Lactiplantibacillus plantarum strain as a biosensor for detecting lung disease by secreting a detectable biomarker in urine.

DOI 10.1101/2023.09.27.559779

mouseexperimental assay

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