BiophysicsbioRxivPreprint
Active site tyrosine residues in human NQO1 homodimer are critical for non-synchronous enzyme catalysis at the two active sites.
Maribel Rivero, Juan Luis Pacheco‐García, Pavla Vaňková…·Angel Luis Pey
This study investigates the role of Tyr126 and Tyr128 in human NQO1 catalysis, showing their critical impact on enzyme activity and non-synchronous catalysis.
DOI 10.1101/2025.02.02.636097