Author

Agnieszka A. Klosowska

University of GdańskORCID 0000-0001-5295-9473Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein sequence· 1

Frequent Co-Authors

Bartłomiej TomiczekiD· 2 shared Dominik PurzyckiiD· 2 shared Hubert WyszkowskiiD· 2 shared Katarzyna KalinowskaiD· 2 shared Agata Konieczna· 1 shared Aneta SzymańskaiD· 1 shared Brenda A. SchilkeiD· 1 shared Elizabeth Anne CraigiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiochemistry

Bartłomiej TomiczekORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintFeb 9, 2026

Multi-Step Hsp70 Recruitment by Class B J-Domain Proteins Drives Efficient Protein Disaggregation

Hubert Wyszkowski, Agata Konieczna, Maria Pokornowska…·Agnieszka A. Klosowska

This study examines how Class B J-Domain Proteins enhance Hsp70-mediated protein disaggregation through autoinhibition and EEVD motif interactions.

DOI 10.64898/2026.02.06.704373

𝕏 PostBluesky

Evolutionary BiologyProceedings of the National Academy of SciencesPeer-reviewedJan 9, 2026

Origin of Class B J-domain proteins involved in amyloid transactions

Przemyslaw Domanski, Milena Stolarska, Katarzyna Kalinowska…·Bartłomiej Tomiczek

This paper investigates the evolutionary origin of class B J-domain proteins, showing they evolved from class A duplicates by losing their zinc finger domain, enabling new functions in amyloid aggregate regulation.

3 citationstop 5%

comparative / phylogenetic analysischromatin & epigenetic regulation

𝕏 PostBluesky