Ran Levi

The paper creates a detailed computational model of rat somatosensory cortex anatomy, including 4.2 million neurons and 14.2 billion synapses, and identifies limitations in connectivity prediction from morphology.

The paper identifies a brain serotonin circuit that contributes to age-related decline in physical activity and shows it can be reversed by targeting specific receptors.

The paper shows that heterogeneous and higher-order cortical connectivity allows neural networks to balance efficiency and robustness by supporting subpopulations with different roles.

The paper shows that synaptic connectivity influences neuronal stimulus encoding, revealing two distinct coding strategies in a microcircuit.