Molecular BiologybioRxivPreprint
A drug combinational therapy consisting of toxin phospholipase A2 and metalloproteinase inhibitors provides preclinical protection against North American Crotalid snakebite envenoming
Charlotte A. Dawson, Amy E. Marriott, Edouard Crittenden…·Nicholas R. Casewell
This study evaluates drug combinations to treat snakebite envenoming, finding that combining SVMP and PLA2 inhibitors provides broad protection against lethal effects.