Rachel H. Clare

This study evaluates repurposed drugs against venoms from the Bothrops snake genus, finding that metalloproteinase inhibitors effectively neutralize multiple venom effects.

This paper develops DC-174, an oral small molecule that inhibits snake venom metalloproteinases and shows efficacy in a mouse model of envenoming.

This study evaluates drug combinations to treat snakebite envenoming, finding that combining SVMP and PLA2 inhibitors provides broad protection against lethal effects.

This study compares venom variation in Bitis arietans across three regions using transcriptomics, chromatography, and functional assays, finding substantial toxin variation but no major impact on antivenom efficacy.