Author

Edouard Crittenden

Liverpool School of Tropical MedicineORCID 0000-0003-1676-5457Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Molecular Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Research Focus:cell type annotation· 1 Organism:mouse· 1 Organism:non-human primate· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

Adam WesthorpeiD· 3 shared Charlotte A. DawsoniD· 3 shared Amy E. MarriottiD· 2 shared Emma L. Stars· 2 shared Nicholas R. CasewelliD· 2 shared Rachel H. ClareiD· 2 shared Rebecca J. EdgeiD· 2 shared Cassandra Marie ModahliD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersBioengineering

Adam WesthorpeORCID

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3 papers

Recent·Most cited

BioengineeringbioRxivPreprintMar 31, 2026

Establishment of snake venom gland organoids from a novel family, Colubridae

Stephanie A. French, Rachael Da Silva, Rohit N. Patel…·Cassandra Marie Modahl

This study establishes venom gland organoids from Colubridae snakes and shows in vitro toxin production.

DOI 10.64898/2026.03.27.714740

non-human primateorganoid / primary culture

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Pharmacology & ToxicologybioRxivPreprintMay 23, 2025

Discovery and Development of DC-174 as a Novel Oral Snakebite Treatment

Daniel J. W. Chong, Laura-Oana Albulescu, Adam Westhorpe…·Paul M. O’Neill

This paper develops DC-174, an oral small molecule that inhibits snake venom metalloproteinases and shows efficacy in a mouse model of envenoming.

4 citations

mouseexperimental assay

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Molecular BiologybioRxivPreprintApr 25, 2025

A drug combinational therapy consisting of toxin phospholipase A2 and metalloproteinase inhibitors provides preclinical protection against North American Crotalid snakebite envenoming

Charlotte A. Dawson, Amy E. Marriott, Edouard Crittenden…·Nicholas R. Casewell

This study evaluates drug combinations to treat snakebite envenoming, finding that combining SVMP and PLA2 inhibitors provides broad protection against lethal effects.

1 citation

experimental assaydrug response / drug discovery

𝕏 PostBluesky