Author

Emma L. Stars

Liverpool School of Tropical Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:mouse· 1

Frequent Co-Authors

Adam WesthorpeiD· 3 shared Nicholas R. CasewelliD· 3 shared Rachel H. ClareiD· 3 shared Amy E. MarriottiD· 2 shared Charlotte A. DawsoniD· 2 shared Edouard CrittendeniD· 2 shared Laura-Oana AlbulescuiD· 2 shared Stefanie K. MenziesiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersMolecular Biology

Adam WesthorpeORCID

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3 papers

Recent·Most cited

Repurposed small molecule toxin inhibitors neutralise a diversity of venoms from the Neotropical viperid snake genus Bothrops

Rachel H. Clare, Adam Westhorpe, Emma L. Stars, Taline D. Kazandjian, Laura-Oana Albulescu, Stefanie K. Menzies, Nicholas R. Casewell

This study evaluates repurposed drugs against venoms from the Bothrops snake genus, finding that metalloproteinase inhibitors effectively neutralize multiple venom effects.

eLife · Jun 30, 2026Peer-reviewedMolecular Biology

Discovery and Development of DC-174 as a Novel Oral Snakebite Treatment

Daniel J. W. Chong, Laura-Oana Albulescu, Adam Westhorpe, Rachel H. Clare, Amy E. Marriott, Christopher M. Woodley, Gunasekar Ramachandran, Nada Mosallam, Edouard Crittenden, Emma L. Stars, Charlotte A. Dawson, Jeroen Kool, Mark C. Wilkinson, Suet C. Leung, Neil G. Berry, , Paul M. O’Neill

This paper develops DC-174, an oral small molecule that inhibits snake venom metalloproteinases and shows efficacy in a mouse model of envenoming.

bioRxiv · May 23, 2025 · PreprintPharmacology & Toxicology

A drug combinational therapy consisting of toxin phospholipase A2 and metalloproteinase inhibitors provides preclinical protection against North American Crotalid snakebite envenoming

Charlotte A. Dawson, Amy E. Marriott, Edouard Crittenden, Adam Westhorpe, Emma L. Stars, Rebecca J. Edge, Steven Robert Hall, Stefanie K. Menzies, Rachel H. Clare, Nicholas R. Casewell

This study evaluates drug combinations to treat snakebite envenoming, finding that combining SVMP and PLA2 inhibitors provides broad protection against lethal effects.

bioRxiv · Apr 25, 2025 · PreprintMolecular Biology