Stéphane Claverol

This study shows that non-toxic iron overload in neuroblastoma cells reprograms mitochondrial and redox metabolism by increasing proton leak and reducing oxidant production.

This study compares mitochondrial function and TCA cycle activity in sheep resistant to atrial fibrillation (AF) versus those that develop stable AF, finding differences in redox state and energy metabolism.

This study shows that TORC1 modulates cohesin functions in chromosome segregation and gene expression, linking environmental changes to chromosome stability.

This study identifies and characterizes TbPat, a triacylglycerol lipase in Trypanosoma brucei, showing its role in lipid mobilization and differentiation.

The paper investigates the role of HID1 in cell proliferation using Schizosaccharomyces pombe, finding that hid1{Delta} mutants exhibit reduced proliferation due to metabolic stress and compromised Golgi function.

This study identifies a unique lipid composition in plant autophagic membranes, showing phosphatidylglycerol's functional role in autophagy activity.

The paper characterizes a VGLUT1 knock-down mouse model and finds that reduced VGLUT1 expression does not significantly affect quantal size or frequency of glutamate release.

The paper develops synthetic binders specific to PSD-95 for imaging endogenous proteins with minimal impact on function and compatibility with super-resolution techniques.

The paper identifies hub synapses in the mouse striatum formed by dopaminergic inputs that connect with glutamatergic, GABAergic, and cholinergic synapses, revealing a new framework for studying neuromodulation.

The paper compares aggregated alpha-synuclein in Parkinson's disease and multiple system atrophy brains to determine their proteomic composition and potential cross-seeding mechanisms.

Stealth α-synuclein fibrils escape ThT detection, outcompete visible polymorphs, and spread neurodegeneratively in vivo.