Yoshiki Yamaryo‐Botté

This paper investigates the role of fatty acid elongases (FAE) in Toxoplasma gondii type II strains, showing their importance for virulence, persistence, and lipid metabolism under stress.

This study shows that acetyl-CoA synthetase (ACAS) in Plasmodium falciparum is essential for nuclear histone acetylation, which regulates gene expression and the transcriptional cycle during the parasite's life cycle.

This study identifies and characterizes TbPat, a triacylglycerol lipase in Trypanosoma brucei, showing its role in lipid mobilization and differentiation.

This study investigates how cardiolipin influences lipid unsaturation and membrane function during anaerobic adaptation in E. coli, revealing its role in optimizing membrane protein function.

This study identifies MMV687794 as an inhibitor of Plasmodium falciparum RBC invasion by targeting PfSLIRP, a rhoptry protein involved in lipid metabolism and vacuole formation.

This study identifies PfAQP's role in glycerol-dependent lipid metabolism, membrane biogenesis, and stress adaptation in Plasmodium falciparum through knockdown and metabolomic analyses.

This study identifies ORP5 as a key regulator of phosphatidic acid partitioning between triacylglycerol and cardiolipin synthesis at MAM-LD junctions, showing its role in balancing lipid metabolism and mitochondrial health.

This study identifies the SUN1-ALLAN complex as critical for coordinating nuclear envelope remodeling and bipartite MTOC segregation during rapid mitosis in Plasmodium male gametogenesis.

This study shows that blocking CSF-1R in tumor-associated macrophages alters their metabolism, enhancing sensitivity to 5-fluorouracil in colorectal cancer.

This study shows that NME1/2 regulate liver response to high-fat diet by repressing de novo lipogenesis and activating protective gene expression through histone acetylation.