NeurosciencebioRxivPreprint
NF-kB/NLRP3 Translational Inhibition by Nanoligomer Therapy Mitigates Ethanol and Advanced Age-Related Neuroinflammation
Paige E. Anton, Prashant Nagpal, Julie A. Moreno…·Rebecca L. McCullough
This study shows that binge ethanol increases NLRP3+ microglia in aged mice, and that Nanoligomer therapy reduces ethanol-induced neuroinflammation and tau hyperphosphorylation.
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