Author

Chen-Jun Guo

ShanghaiTech UniversityORCID 0000-0001-5342-4761Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Approach:microscopy & imaging analysis· 1 Assay:protein structure· 1

Frequent Co-Authors

Ji‐Long LiuiD· 2 shared Rui Ying WangiD· 1 shared Shaorong GaoiD· 1 shared Tianyi Zhang· 1 shared Xian ZhouiD· 1 shared Xiaojie BaoiD· 1 shared Yawei GaoiD· 1 shared Yi‐Lan LiiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

Ji‐Long LiuORCID

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2 papers

Recent·Most cited

Cell BiologyExperimental Cell ResearchPeer-reviewedJul 1, 2025

FMR1 KH0-KH1 Domains Coordinate m6A Binding and Phase Separation in Fragile X Syndrome

Xian Zhou, Chen-Jun Guo, Rui Ying Wang…·Yawei Gao

This study shows KH0 and KH1 domains of FMR1 work together in m6A binding and phase separation, linking these processes to Fragile X Syndrome pathology.

2 citations

humanprotein structure

𝕏 PostBluesky

BiochemistrybioRxivPreprintFeb 22, 2025

CTP Drives Human CTPS1 Filamentation

Chen-Jun Guo, Xiaojie Bao, Ji‐Long Liu

This study identifies CTP as a regulator of hCTPS1 filamentation, revealing its structural basis and evolutionary conservation.

1 citation

humancryo-EM

𝕏 PostBluesky