Author

Jean‐Claude Alvarez

InsermORCID 0000-0001-5344-9475Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Alain Michel GardieriD· 1 shared Céline DefaixiD· 1 shared Christine Ann DennyiD· 1 shared Denis Joseph Paul DavidiD· 1 shared Emmanuelle CorrubleiD· 1 shared Indira Mendez‐DavidiD· 1 shared Isabelle Etting· 1 shared Jaclyn N. HighlandiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Alain Michel GardierORCID

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1 paper

Recent·Most cited

NeuroscienceNeuropharmacologyPeer-reviewedJul 14, 2024

Ketamine metabolism via hepatic CYP450 isoforms contributes to its sustained antidepressant actions.

Thi Mai Loan Nguyen, Jean‐Philippe Guilloux, Céline Defaix…·Alain Michel Gardier

The paper investigates how ketamine's metabolism via hepatic CYP450 enzymes affects its antidepressant effects, finding that (6)-HNKs mediate sustained antidepressant actions.

3 citations

mousestatistical model

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