Author

Emmanuelle Corruble

InsermORCID 0000-0002-9441-6079Unclaimed ORCID profile · follow to get notified of new preprints

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1

Frequent Co-Authors

Denis Joseph Paul DavidiD· 2 shared Alain Michel GardieriD· 1 shared Ali Saffet GönüliD· 1 shared Alyssa R. AmodiD· 1 shared Angelica M. Minier-ToribioiD· 1 shared Aslihan Uyar-DemiriD· 1 shared Baptiste Couvy‐DuchesneiD· 1 shared Bianca BesteheriD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersNeuroscience

Denis Joseph Paul DavidORCID

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3 papers

Recent·Most cited

Neural correlates in basolateral and central amygdala during reward seeking in the face of punishment

Angelica M. Minier-Toribio, Brian F Sadacca, Emmanuelle Corruble, Denis Joseph Paul David, Yavin Shaham, Geoffrey M. Schoenbaum, Yann Pelloux

This study examines neural activity in the basolateral and central amygdala during reward seeking under punishment, finding that opposing neuronal populations in the CeA control reward-seeking behavior despite adverse consequences.

bioRxiv · Mar 26, 2025 · PreprintNeuroscience

Ketamine metabolism via hepatic CYP450 isoforms contributes to its sustained antidepressant actions.

Thi Mai Loan Nguyen, Jean‐Philippe Guilloux, Céline Defaix, Indira Mendez‐David, Isabelle Etting, Jean‐Claude Alvarez, Josephine Cecelia McGowan, Jaclyn N. Highland, Panos Zanos, Jacqueline Lovett, Ruin Moaddel, Emmanuelle Corruble, Denis Joseph Paul David, Todd D. Gould, Christine Ann Denny, Alain Michel Gardier

The paper investigates how ketamine's metabolism via hepatic CYP450 enzymes affects its antidepressant effects, finding that (6)-HNKs mediate sustained antidepressant actions.

Neuropharmacology · Jul 14, 2024Peer-reviewedNeuroscience

A Large-Scale ENIGMA Multisite Replication Study of Brain Age in Depression

Laura K. M. Han, Richard Dinga, Ramona Leenings, Tim Hahn, James Howard Cole, Lyubomir I. Aftanas, Alyssa R. Amod, Bianca Besteher, Romain Colle, Emmanuelle Corruble, Baptiste Couvy‐Duchesne, Konstantin V. Danilenko, Paola Fuentes‐Claramonte, Ali Saffet Gönül, Ian H. Gotlib, , Lianne Schmaal

The paper replicates a brain age gap in depression using a large-scale multisite study, finding a similar effect size to a prior study.

Neuroimage Reports · Nov 29, 2022Peer-reviewedNeuroscience